CARD-02

Novel multiscale and multisystem approaches to cardiovascular modeling and simulation (Part 1)

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Organizers:

Mitchel J. Colebank (University of South Carolina), Vijay Rajagopal, The University of Melbourne, Australia

Description:

Cardiovascular models are now recognized as a potential frontier in the development of personalized models and digital twins. This new excitement in the field is fueling new strides in mathematical and computational approaches to describe cardiovascular function across different temporal and/or spatial scales. In addition, new multisystem models accounting for how the heart and vasculature interact with other organ systems are being developed in combination with tools located at the heart of data science. Thus, this minisymposium will focus on the development of cardiovascular models that mimic cardiovascular function across spatial or temporal scale, new models that couple the cardiovascular system with other physiological systems, and new innovations in data-driven solutions to modeling cardiovascular phenomena. Potential topics include: - Multiscale models of cardiac and vascular function; - Computational approaches to cell-tissue-organ level function; - Mathematical coupling of cardiac and vascular mechanics; - Modeling autonomic control and neurovascular function; - Simulating tissue growth and remodeling; - Multisystems models of cardiovascular-organ interactions; and - Physics-informed data science approaches to cardiovascular science

Diversity Statement:

The organizers actively sought speakers in the 6 major continents and did not discriminate by race or gender. Given the location of SMB in North America, our current speaker list includes multiple contributors from the USA (8), as well as the United Kingdom (2), Australia (2), and one from Asia. We also sought a diverse background of speakers, and recognize that more effort is required to bring in both female researchers and those from Asia, Africa, and South America.



Mitchel J. Colebank (University of South Carolina)

"“Effects of vasomotor tone on systemic vascular wave reflections”"



Alyssa Taylor-Lapole (Rice University)

"A discontinuous Galerkin approximation for a 3D-1D advection-diffusion model to investigate liver perfusion."



Stephen Payne (National Taiwan University & University of Oxford)

"Multiscale models of cerebral blood flow and metabolism"



Karin Leiderman (University of North Carolina, Chapel Hill)

"A discrete platelet-bonding model for simulating platelet aggregation under flow"



Noelia Grande Gutiérrez (Carnegie Mellon University)

"Multiscale modeling of thrombosis formation"



Mette Olufsen (North Carolina State University)

"An uncertainty aware framework for generating vascular networks from imaging"



Pim Oomen (University of California, Irvine)

"Systems biology modeling of sex hormone-driven cardiac remodeling"



Pak-Wing Fok (University of Delaware)

"Effect of medial arterial calcification on hemodynamics: mechanisms and insights"



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Annual Meeting for the Society for Mathematical Biology, 2025.