IMMU-04

Multiscale modelling in infectious diseases

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Organizers:

Dr Macauely Locke (Los Alamos National Laboratory), Dr Jasmine Kreig, Dr Aurelien Marc, Los Alamos National Laboratory

Description:

Part of the complexity of biological and epidemiological systems arises from interactions that occur on different scales. This mini-symposium explores available data scales and how models can be formulated to represent them, with applications to viral dynamics, immune responses, and epidemiology. In addition to showcasing current work by presenters, this session encourages discussion of further development on and novel approaches to multiscale modelling of infectious diseases. This session aims to gather speakers from diverse backgrounds, including early and late-career scientists and post-docs, different fields of expertise such as viral dynamics, immunology (T-cell and antibody) and epidemiology and cover a range of institutions (such as Academia and National labs).

Diversity Statement:

We have aimed to be an inclusive mini-symposium by including many diverse backgrounds, skill levels and professional levels of development. We contacted potential speakers from many countries to bring together scientists and researchers from different cultural backgrounds. We also made sure to be an inclusive organising committee to represent the scientific community best.



Dr Daniel Luque-Duque (Imperial College London)

"Estimating the evolution of thymic output for $alphabeta$ and $gammadelta$ populations using TCR sequencing data."



Professor Grant Lythe (University of Leeds)

"Models of bursting and budding"



Dr Sarafa Iyaniwura (Fred Hutch)

"Understanding the dynamics of chronic Hepititis B virus during therapy"



Dr Aurelien Marc (Los Alamos National Labratory)

"Mechanistic modelling of clinical trials in HCV patients: evaluation of efficacy of Bemnifosbuvir and Ruzasvir"



Dr Mason Lacy (Queensland University of Technology)

"Individual-based and continuum models for understanding ex vivo T cell expansion"



Dr Nathanael Hoze (IAME)

"Integrating multiscale mathematical modeling and serology to unravel antibody dynamics and infection risk"



Dr Paolo Bosetti (Pasteur institute)

"Statistical and mathematical methods to characterize disease transmission from incomplete epidemiological data"



Dr Quiyana Murphey (Virginia tech)

"Antibody magnitude and durability following vaccination against SARS-CoV-2"



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Annual Meeting for the Society for Mathematical Biology, 2025.