PS01 ONCO-04

Modeling Metastatic Cancer Treatment with Neoantigen Peptide Vaccine

Monday, July 14 at 6:00pm in

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Jessica Kingsley

University of Tennessee-Knoxville
"Modeling Metastatic Cancer Treatment with Neoantigen Peptide Vaccine"
We begin with a system of ordinary differential equations for an immunological treatment of a primary tumor by neoantigen peptide vaccines. This system is coupled with a partial differential equation of metastasis that tracks the number of metastases per time and size. Vaccine dose is taken as a control in the primary tumor ordinary differential equation to slow tumor growth and the spread of metastatic tumors. An optimal control problem is formulated to design vaccine treatment.


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Annual Meeting for the Society for Mathematical Biology, 2025.