PS01 ONCO-13

Modelling interclonal cooperation in epithelial carcinogenesis using a vertex-based approach

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Muhammad Farooq

The University of Sydney
"Modelling interclonal cooperation in epithelial carcinogenesis using a vertex-based approach"
This study uses a vertex-based computational model based on CHASTE to investigate interclonal cooperation within cell populations. We analyze interactions between mutated cell types with distinct hyperproliferative and invasive properties. Modeling the cooperative dynamics between these clones shows how cellular heterogeneity affects tissue growth and invasion, enhancing the understanding of tumor progression and therapeutic target predictions.


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Annual Meeting for the Society for Mathematical Biology, 2025.