CDEV-01

Mathematical and computational ophthalmology: insights from data-driven multiscale modelling of the eye

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Organizers:

Laura Wadkin (Newcastle University), Patrick Parkinson (Newcastle University)

Description:

Mathematical ophthalmology is a novel and rapidly evolving interdisciplinary field in which diverse techniques across mathematics are applied to deepen our understanding of the formation, structure, and function of the eye during development, health, and disease. Mathematical and computational models are driving technological advances in diagnostic tools for clinicians, predicting and monitoring disease progression, and deepening our understanding of the physiology of the eye. In this mini-symposium, our speakers will present some of the cutting-edge research across this area, highlighting how mathematics can contribute to solving complex biological and medical problems. Themes covered will include (but not be limited to): harnessing clinical trial image data, quantifying diagnostic cellular characteristics, agent-based modelling, continuum modelling, collective cellular behaviours, wound healing, and ocular drug delivery.

Diversity Statement:

We prioritised equality, diversity and inclusion in the organisation of our mini-symposium to platform diverse groups, enrich discussion and encourage broader representation in this field. Our speakers span a range of backgrounds and career stages, with three talented early-career researchers. We have strongly considered gender balance; half of our speakers, plus the lead organiser identify as women. We strive to create a supportive forum where all attendees are empowered to share their ideas.



Patrick Parkinson (Newcastle University)

"Optimising stem cell therapies for corneal damage: insights from clinical trial image analysis and mathematical modelling"



Katie Bentley (Francis Crick Institute)

"Integrating agent-based modelling with patient OCT-A imaging to understand diabetic retinopathy vascular dynamics"



Joel Vanin (Indiana University Bloomington)

"An Agent-Based Computational Framework for Simulating Corneal Biology: A Platform for Multi-Scale Investigation of Homeostasis and Wound Healing"



Patricia Lamirande (University of Oxford)

"A mean first passage time approach to quantify ocular drug delivery and residence time"



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Annual Meeting for the Society for Mathematical Biology, 2025.