Organizers:
James Osborne (University of Melbourne), James Glazier (Indiana University) Yi Jiang (Georgia State University)
Description:
Multicellular simulations have become indispensable in understanding complex biological phenomena, from tissue development to disease progression. But the diversity in simulation methods - from agent-based models, lattice-free models, stochastic particle simulations, etc - poses challenges in reproducibility, modularity, reusability, and integration within multi-scale simulation. This minisymposia aims to present the variety of multicellular simulations being used by the community along with the efforts to make these simulations replicable and reproducible. Through a series of scientific presentations, we will demonstrate the need for standardization, and the importance of sharing and reusing models. The minisymposia is broken up into three parts; Parts 1 and 2: Modelling Biological Systems 1 and 2. Part 3: Reproducibility and Standards. Parts 1 and 2 of the Minisymposia (Modelling Biological Systems 1 and 2) contain a series of scientifically focused talks to demonstrate the variety of modelling techniques and applications being used in multicellular simulations. These talks have a scientific focus however each talk will have 5 minutes dedicated to model specification/reproducibility/comparison. Part 3 of the Minisymposia (Reproducibility and Standards) contains a series of talks on the current efforts in reproducibility and standards for multicellular simulations including a report on the OpenVT Satellite meeting reproducibility challenge.
Claire Miller
Auckland Bioengineering Institute, NEW ZEALAND"Multicellular modelling of endometrial cell invasion in endometriosis lesion onset"
TJ Sego
University of Florida, USA"Quantitative Reproducibility at Scale: A Federated, Standardizable Approach"
Steve Runser
ETH Zurich, SWITZERLAND"PolyHoop & SimuCell3D: Efficient and Versatile Tissue Simulations in 2D and 3D"
Eran Agmon
University of Connecticut, USA"Multicellular Schema with Vivarium"
