NEUR-02

Modeling of Neurodegenerative Diseases

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Organizers:

Laurent PUJO-MENJOUET and Suzanne SINDI (Claude Bernard Lyon 1 University (Lyon, FRANCE))

Description:

This mini-symposium focuses on the mathematical modeling of neurodegenerative diseases, including Alzheimer's, Creutzfeldt-Jakob, and Parkinson's, among others. The approaches discussed may span various scales, ranging from molecular (such as protein dynamics) to cellular (e.g., intercellular communication) and tissue-level phenomena (e.g., the spread of pathologies in specific brain regions or the formation of amyloid plaques). The mathematical tools explored during the symposium comprise a wide range, including ordinary and delayed differential equations, partial differential equations with diverse structures (e.g., size, spatial, or hybrid models), and advanced techniques such as neural networks for image analysis and data augmentation. By addressing all scales and employing a variety of methods, this mini-symposium aims to shed light on the complex mechanisms underlying these often fatal diseases, which continue to pose significant scientific challenges and unanswered questions.

Diversity Statement:

In organizing our mini-symposium, our goal was to ensure an inclusive environment for all participants, regardless of race, color, sex, gender, sexual orientation, gender identity, gender expression, religion, national origin, age, or disability. Gender parity has been maintained within the organizing team, and the participants represent a rich diversity of cultural backgrounds, sexual orientations, races, and ethnicities. We are deeply committed to honoring this diversity throughout the event.



Théo LOUREAUX (University of California, MERCED)

"A New Data Augmentation Method: Synthetic Biological Images for Deep-Learning Models"



Ashish RAJ (University of California, SAN FRANCISCO)

"Biophysical modeling of pathology progression in dementia and its implementation using physics-informed neural networks"



Human REZAEI (INRAE Center, Jouy-en-Josas)

"The dynamics of prion spreading is governed by the interplay between the non-linearities of tissue response and replication kinetics"



Laurent PUJO-MENJOUET (Claude Bernard Lyon 1 University)

"A multigroup approach to delayed prion production"



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Annual Meeting for the Society for Mathematical Biology, 2025.